How to Replay Completed Missions in Assassins Creed 2by Melissa King ; Updated September 22, 2017
In "Assassin's Creed 2," you play as Ezio Auditore da Firenze , a man who swears to get revenge on those responsible for murdering his brother and father. His quest leads him to become part of an ancient order of assassins. During the game, you are presented with many types of missions. Story missions advance the quest and lead Ezio closer to the truth. Once completed, you cannot play these missions again. Side missions, such as races and assassinations, are re-playable, however.
Complete a side mission to add it to your Secondary Memories list. Side missions are marked by various icons on your map.
Pause the game and select "DNA." Scroll to and select "Secondary Memories."
Use the directional pad to scroll through all of your completed missions. Select the desired mission to replay it.
"Assassin's Creed: Brotherhood" is the only game in the series that lets you replay story missions (at the time of this writing).